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New Adventist Study on Stroke Preventing Therapy
From
"Christian B. Schäffler" <APD_Info_Schweiz@compuserve.com>
Date
13 Feb 1999 09:09:54
February 12, 1999
Adventist Press Service (APD)
Christian B. Schaeffler, Editor-in-chief
Fax +41-61-261 61 18
APD@stanet.ch
CH-4003 Basel, Switzerland
New Adventist Study on Stroke Preventing Therapy:
Research Suggests Patients Over Age 80 May Have a
Better Option Than Surgery
Takoma Park, MD/USA. [APD] Preliminary research
conducted by a nationally known cardiologist
suggests that a therapeutic procedure designed to
prevent stroke is equally effective for patients
over the age of 80 who are at higher risk for stroke
and death compared to patients under the age of 80.
"The results may imply that the procedure, stent
supported carotid angioplasty, may be a safer option
than surgery for patients over age 80 with a high risk
of stroke," noted Fayaz A. Shawl, M.D., Director of
Interventional Cardiology at Washington Adventist
Hospital (WAH).
Dr. Shawl and colleagues examined the combined use of
carotid angioplasty and stents in 140 patients between
1995 and early 1998. Using a non-surgical procedure,
the doctors insert a balloon-bearing catheter into the
carotid artery (in the neck) to open blockages. Upon
opening the artery, the catheter makes space for a
tube-like stent to hold open the artery that allows
blood to continue flowing to the brain.
Washington Adventist Hospital (WAH) is one of only a
few U.S. medical centers investigating the procedure,
which is being researched as an alternative to the
carotid endarterectomy, a surgical procedure which
involves anesthesia, an incision in the neck and
removal of plaque from the artery.
Carotid endarterectomy has been associated with
significant morbidity and mortality in patients,
particularly patients age 80 or older. Carotid
stenting may be a viable option for such patients who
are ineligible for carotid endarterectomy. Both
traditional carotid endarterectomy and this research
procedure using carotid angioplasty carry risks that
include bleeding at the site of the procedure, possible
slight or even major stroke, or death. It is not yet
known if these risks are less or greater with the
research procedure compared to carotid endarterectomy.
Potential benefits of the procedure include rapid
recovery and reduced costs. Patients are awake
throughout the procedure and most require only a
twenty-four hour hospital stay.
Carotid artery disease is believed to be responsible
for sixty percent of strokes annually. This research
procedure may enable doctors to intervene and prevent
or reduce the number of strokes caused by carotid
artery disease.
The patient mix of the WAH study consisted of 34
patients over the age of 80 and 105 patients below the
age of 80. While not examined by the study, the
authors hypothesize that the successful outcomes were
supported by intensive therapy prior to treatment to
reduce a patient's risk of stroke.
"Our data demonstrate that stent supported carotid
angioplasty is safe and effective for all age groups
from the 215 patients we have done to date," said Dr.
Shawl. "But it is noteworthy that in our study the
age group over 80 has done as well as the younger
patients. Usually, these patients are not offered
standard surgical treatment (endarterectomy) because
of the high risk of procedural complications of death
and stroke."
In the carotid angioplasty procedure, a balloon-
bearing catheter is inserted in the femoral artery in
the groin and guided through the blood vessels in the
abdomen and chest into the carotid arteries. The
balloon is inflated two to four times to push back the
blockage and make space for implantation of the stent.
(A stent is a tiny, stainless steel tube which, when
expanded by the balloon on the catheter, holds the
vessel open, like a scaffold). The catheter is then
removed, equipped with a peripheral stent and
reinserted. The balloon is inflated and the stent
implanted, and the catheter is removed. Clearing the
blockage of the artery restores blood flow to the
brain.
Located in Takoma Park, Maryland, Washington Adventist
Hospital offers a complete range of cardiac care
services, including research, risk reduction,
diagnosis, arrhythmia management, intervention,
surgery and rehabilitation. Founded in 1907,
Washington Adventist Hospital performs more than 900
open heart surgeries a year and more than 5,000 heart
catheterizations and angioplasties. [99/02/07]
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